Also procainamide-induced antinuclear antibodies are formed after a 6 months treatment.
2.
Dermatomyositis is associated with autoantibodies, especially antinuclear antibodies ( ANA ).
3.
Lupus patients, for instance, often make too much of an antibody called ANA, or antinuclear antibody.
4.
The first evidence for antinuclear antibodies arose in 1948 when Hargraves, Richmond and Morton discovered the LE cell.
5.
But further research showed, that after a long-term therapy of procainamide, some subjects did not produce any antinuclear antibodies.
6.
Antinuclear antibodies cause an inflammation in the uterus that does not allow it to be a suitable host for implantation of the embryo.
7.
Antinuclear antibodies ( ANA )-A negative ANA is a good test to rule out lupus, but a positive result is not reliable in confirming lupus.
8.
Typical scleroderma is classically defined as symmetrical skin thickening, with about 70 % of cases also presenting with Raynaud's phenomenon, nail-fold capillary changes and antinuclear antibodies.
9.
The diagnosis is made with Immunofluorescence techniques, which shows circulating and tissue-bound autoantibodies ( particulate stratified squamous-epithelium-specific antinuclear antibody ) to DeltaNp63alpha protein, a normal component of the epithelium.
10.
ESR was elevated at 35 mm / hour; cardiolipin IgM was weakly positive at 16.3; C4 was decreased at 10 mg / dl; antinuclear antibodies were negative and p-ANCA was reactive.
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